Cargando…

Ginkgolic acid inhibits HIV protease activity and HIV infection in vitro

BACKGROUND: Several HIV protease mutations, which are resistant to clinical HIV protease inhibitors (PIs), have been identified. There is a great need for second-generation PIs with different chemical structures and/or with an alternative mode of inhibition. Ginkgolic acid is a natural herbal substa...

Descripción completa

Detalles Bibliográficos
Autores principales:	Lü, Jian-Ming, Yan, Shaoyu, Jamaluddin, Saha, Weakley, Sarah M., Liang, Zhengdong, Siwak, Edward B., Yao, Qizhi, Chen, Changyi
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	International Scientific Literature, Inc. 2012
Materias:	Basic Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3560711/ https://www.ncbi.nlm.nih.gov/pubmed/22847190 http://dx.doi.org/10.12659/MSM.883261

Ejemplares similares

Nordihydroguaiaretic acid (NDGA) inhibits ritonavir-induced endothelial dysfunction in porcine pulmonary arteries
por: Lü, Jian-Ming, et al.
Publicado: (2011)

Resistin Increases Monolayer Permeability of Human Coronary Artery Endothelial Cells
por: Jamaluddin, Md Saha, et al.
Publicado: (2013)

Transforming growth factor-β increases the expression of vascular smooth muscle cell Markers in human multi-lineage progenitor cells
por: Yang, Hui, et al.
Publicado: (2011)

Natural antioxidant dihydroxybenzyl alcohol blocks ritonavir-induced endothelial dysfunction in porcine pulmonary arteries and human endothelial cells
por: Weakley, Sarah M., et al.
Publicado: (2011)

Ginsenoside Rb1 Blocks Ritonavir-Induced Oxidative Stress and eNOS Downregulation through Activation of Estrogen Receptor-Beta and Upregulation of SOD in Human Endothelial Cells
por: Lü, Jian-Ming, et al.
Publicado: (2019)

Ginkgolic acid inhibits fusion of enveloped viruses
por: Borenstein, Ronen, et al.
Publicado: (2020)

Ginkgolic acid suppresses the development of pancreatic cancer by inhibiting pathways driving lipogenesis
por: Ma, Jiguang, et al.
Publicado: (2015)

Author Correction: Ginkgolic acid inhibits fusion of enveloped viruses
por: Borenstein, Ronen, et al.
Publicado: (2020)

Ginkgolic acid and anacardic acid are specific covalent inhibitors of SARS-CoV-2 cysteine proteases
por: Chen, Zinuo, et al.
Publicado: (2021)

Synthesis of Ginkgolic Acid Analogues and Evaluation of Their Molluscicidal Activity
por: Zhang, Peng, et al.
Publicado: (2011)

MicroRNA-196: critical roles and clinical applications in development and cancer
por: Chen, Changyi, et al.
Publicado: (2011)

Pharmacological Activities of Ginkgolic Acids in Relation to Autophagy
por: Ding, Yuan, et al.
Publicado: (2022)

Ginkgolic acid and anacardic acid are reversible inhibitors of SARS-CoV-2 3-chymotrypsin-like protease
por: Li, Dongsheng, et al.
Publicado: (2022)

Two Antibody-Guided Lactic-co-Glycolic Acid-Polyethylenimine (LGA-PEI) Nanoparticle Delivery Systems for Therapeutic Nucleic Acids
por: Lü, Jian-Ming, et al.
Publicado: (2021)

HIV protease inhibitors disrupt astrocytic glutamate transporter function and neurobehavioral performance
por: Vivithanaporn, Pornpun, et al.
Publicado: (2016)

Ginkgolic acid inhibits the invasiveness of colon cancer cells through AMPK activation
por: Qiao, Lina, et al.
Publicado: (2017)

Isovitexin Inhibits Ginkgolic Acids-Induced Inflammation Through Downregulating SHP2 Activation
por: Zhang, Yiwei, et al.
Publicado: (2021)

Ginkgolic acid improves bleomycin-induced pulmonary fibrosis by inhibiting SMAD4 SUMOylation
por: Yu, Lan, et al.
Publicado: (2022)

Selective potentiation of alpha 1 glycine receptors by ginkgolic acid
por: Maleeva, Galyna, et al.
Publicado: (2015)

Ginkgolic acid specifically potentiates alpha 1 glycine receptors
por: Maleeva, Galyna, et al.
Publicado: (2015)

The antibacterial activity and mechanism of ginkgolic acid C15:1
por: Hua, Zhebin, et al.
Publicado: (2017)

Cyclophilin A enhances cell proliferation and tumor growth of liver fluke-associated cholangiocarcinoma
por: Obchoei, Sumalee, et al.
Publicado: (2011)

Ginkgolic Acid Inhibits Coronavirus Strain 229E Infection of Human Epithelial Lung Cells
por: Bhutta, Maimoona S., et al.
Publicado: (2021)

Ginkgolic acids inhibit migration in breast cancer cells by inhibition of NEMO sumoylation and NF-κB activity
por: Hamdoun, Sami, et al.
Publicado: (2017)

Ginkgolic Acid (GA) Inhibits the Growth of OCa by Inhibiting lncRNA MALAT1/JAK2 Axis
por: Fei, Zhiyi, et al.
Publicado: (2021)

Entacapone is an Antioxidant More Potent than Vitamin C and Vitamin E for Scavenging of Hypochlorous Acid and Peroxynitrite, and the Inhibition of Oxidative Stress-Induced Cell Death
por: Chen, Aaron Y., et al.
Publicado: (2016)

Sublingual Immunization with Chimeric C1q/CD40 Ligand/HIV Virus-like Particles Induces Strong Mucosal Immune Responses against HIV
por: Liu, Dongliang, et al.
Publicado: (2021)

Ginkgolic acid inhibits the growth of renal cell carcinoma cells via inactivation of the EGFR signaling pathway
por: Zhu, Chao, et al.
Publicado: (2020)

Ginkgolic Acid Protects against Aβ-Induced Synaptic Dysfunction in the Hippocampus
por: Mango, Dalila, et al.
Publicado: (2016)

Ginkgolic Acid Inhibits Herpes Simplex Virus Type 1 Skin Infection and Prevents Zosteriform Spread in Mice
por: Bhutta, Maimoona S., et al.
Publicado: (2021)

Structure–Activity Relationship of Synthetic Ginkgolic Acid Analogs for Treating Type 2 Diabetes by PTPN9 Inhibition
por: Kim, Jinsoo, et al.
Publicado: (2022)

Highly active antiretroviral therapy drugs inhibit in vitro cholesterol efflux from human macrophage-derived foam cells
por: Wang, Xinwen, et al.
Publicado: (2009)

Ginkgolic acids induce HepG2 cell death via a combination of apoptosis, autophagy and the mitochondrial pathway
por: Qi, Qian-Ming, et al.
Publicado: (2018)

Broad Antiviral Activity of Ginkgolic Acid against Chikungunya, Mayaro, Una, and Zika Viruses
por: Campos, Dalkiria, et al.
Publicado: (2020)

Ginkgolic acids inhibit SARS-CoV-2 and its variants by blocking the spike protein/ACE2 interplay
por: Xiang, Yusen, et al.
Publicado: (2023)

Hyperuricemia-Related Diseases and Xanthine Oxidoreductase (XOR) Inhibitors: An Overview
por: Chen, Changyi, et al.
Publicado: (2016)

A Novel Prime and Boost Regimen of HIV Virus-Like Particles with TLR4 Adjuvant MPLA Induces Th1 Oriented Immune Responses against HIV
por: Poteet, Ethan, et al.
Publicado: (2015)

Mesothelin and TGF-α predict pancreatic cancer cell sensitivity to EGFR inhibitors and effective combination treatment with trametinib
por: Poteet, Ethan, et al.
Publicado: (2019)

Ginkgolic Acid, a SUMO-1 Inhibitor, Inhibits the Progression of Oral Squamous Cell Carcinoma by Alleviating SUMOylation of SMAD4
por: Liu, Ke, et al.
Publicado: (2019)

Gut-dependent inflammation and alterations of the intestinal microbiota in individuals with perinatal HIV exposure and different HIV serostatus
por: Tincati, Camilla, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_128ulgnitg4lq2o28rm9lo46jd