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Selective COX-2 inhibitor ameliorates osteoarthritis by repressing apoptosis of chondrocyte

BACKGROUND: Celecoxib has a positive effect on human osteoarthritic cartilage, but the mechanisms remain unclear. The aim of this study was to test whether celecoxib could inhibit the apoptosis of chondrocyte and ameliorate type II collagen synthesis to relieve symptoms of OA (osteoarthritis). MATER...

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Detalles Bibliográficos
Autores principales: Ou, Yunsheng, Tan, Chao, An, Hong, Jiang, Dianming, Quan, Zhengxue, Tang, Ke, Luo, Xiaoji
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Scientific Literature, Inc. 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3560736/
https://www.ncbi.nlm.nih.gov/pubmed/22648246
http://dx.doi.org/10.12659/MSM.882901