Cargando…
Selective COX-2 inhibitor ameliorates osteoarthritis by repressing apoptosis of chondrocyte
BACKGROUND: Celecoxib has a positive effect on human osteoarthritic cartilage, but the mechanisms remain unclear. The aim of this study was to test whether celecoxib could inhibit the apoptosis of chondrocyte and ameliorate type II collagen synthesis to relieve symptoms of OA (osteoarthritis). MATER...
Autores principales: | Ou, Yunsheng, Tan, Chao, An, Hong, Jiang, Dianming, Quan, Zhengxue, Tang, Ke, Luo, Xiaoji |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
International Scientific Literature, Inc.
2012
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3560736/ https://www.ncbi.nlm.nih.gov/pubmed/22648246 http://dx.doi.org/10.12659/MSM.882901 |
Ejemplares similares
-
Nanohydroxyapatite/polyamide 66 strut subsidence after one-level corpectomy: underlying mechanism and effect on cervical neurological function
por: Zhong, Weiyang, et al.
Publicado: (2018) -
Comparison of osteotomy versus non-osteotomy approach for congenital scoliosis: a retrospective study of three surgical techniques
por: Li, Shenghua, et al.
Publicado: (2015) -
Tranexamic acid reduces perioperative blood loss of posterior lumbar surgery for stenosis or spondylolisthesis: A randomized trial
por: Shi, Houyin, et al.
Publicado: (2017) -
Pleiotropic roles of metallothioneins as regulators of chondrocyte apoptosis and catabolic and anabolic pathways during osteoarthritis pathogenesis
por: Won, Yoonkyung, et al.
Publicado: (2016) -
Melatonin, a novel selective ATF-6 inhibitor, induces human hepatoma cell apoptosis through COX-2 downregulation
por: Bu, Li-Jia, et al.
Publicado: (2017)