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Low dose morphine adjuvant therapy for enhanced efficacy of antipsychotic drug action: Potential involvement of endogenous morphine in the pathophysiology of schizophrenia

Major thematic threads linking extensive preclinical and clinical efforts have established a working mechanistic scheme whereby atypical antipsychotic drugs ameliorate negative DSM IV diagnostic criteria by effecting relatively potent blockade of serotonin (5-HT)(2A) receptors coupled with weaker an...

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Detalles Bibliográficos
Autores principales: Stefano, George B., Králíčková, Milena, Ptacek, Radek, Kuzelova, Hana, Esch, Tobias, Kream, Richard M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Scientific Literature, Inc. 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3560770/
https://www.ncbi.nlm.nih.gov/pubmed/22739740
http://dx.doi.org/10.12659/MSM.883192