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Small interfering RNA-mediated downregulation of β-catenin inhibits invasion and migration of colon cancer cells in vitro

BACKGROUND: Abnormal regulation of Wnt/β-catenin signaling and subsequently increased β-catenin expression have been found to be involved in the proliferation and growth of colon cancer cells. Whether the down-regulation of β-catenin in colon cancer may result in compromised invasion and migration i...

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Detalles Bibliográficos
Autores principales: Han, Jianjun, Gao, Binbin, Jin, Xing, Xu, Zhongfa, Li, Zengjun, Sun, Yanlai, Song, Bao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Scientific Literature, Inc. 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3560771/
https://www.ncbi.nlm.nih.gov/pubmed/22739727
http://dx.doi.org/10.12659/MSM.883205