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Altered expression of base excision repair genes in response to high glucose-induced oxidative stress in HepG2 hepatocytes

BACKGROUND: It is widely accepted that chronic hyperglycemia induces DNA oxidative damage in type 2 diabetes, but little is known about the effect of hyperglycemia on the DNA repair system which plays a critical role in the maintenance of genomic DNA stability in diabetes. MATERIAL/METHODS: To inves...

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Detalles Bibliográficos
Autores principales: Pang, Jing, Xi, Chao, Dai, Yang, Gong, Huan, Zhang, Tie-mei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Scientific Literature, Inc. 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3560773/
https://www.ncbi.nlm.nih.gov/pubmed/22739728
http://dx.doi.org/10.12659/MSM.883206