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Altered expression of base excision repair genes in response to high glucose-induced oxidative stress in HepG2 hepatocytes
BACKGROUND: It is widely accepted that chronic hyperglycemia induces DNA oxidative damage in type 2 diabetes, but little is known about the effect of hyperglycemia on the DNA repair system which plays a critical role in the maintenance of genomic DNA stability in diabetes. MATERIAL/METHODS: To inves...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
International Scientific Literature, Inc.
2012
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3560773/ https://www.ncbi.nlm.nih.gov/pubmed/22739728 http://dx.doi.org/10.12659/MSM.883206 |