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A novel asymmetric-loop molecular beacon-based two-phase hybridization assay for accurate and high-throughput detection of multiple drug resistance-conferring point mutations in Mycobacterium tuberculosis

The accurate and high-throughput detection of drug resistance-related multiple point mutations remains a challenge. Although the combination of molecular beacons with bio-immobilization technology, such as microarray, is promising, its application is difficult due to the ineffective immobilization o...

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Detalles Bibliográficos
Autores principales: Chen, Qinghai, Wu, Nan, Xie, Meng, Zhang, Bo, Chen, Ming, Li, Jianjun, Zhuo, Lisha, Kuang, Hong, Fu, Weiling
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Scientific Literature, Inc. 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3560835/
https://www.ncbi.nlm.nih.gov/pubmed/22460100
http://dx.doi.org/10.12659/MSM.882602