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PDX1-engineered embryonic stem cell-derived insulin producing cells regulate hyperglycemia in diabetic mice
BACKGROUND: Type 1 diabetes can be treated by the transplantation of cadaveric whole pancreata or isolated pancreatic islets. However, this form of treatment is hampered by the chronic shortage of cadaveric donors. Embryonic stem (ES) cell-derived insulin producing cells (IPCs) offer a potentially n...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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BioMed Central
2012
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3560994/ https://www.ncbi.nlm.nih.gov/pubmed/23369186 http://dx.doi.org/10.1186/2047-1440-1-19 |