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PDX1-engineered embryonic stem cell-derived insulin producing cells regulate hyperglycemia in diabetic mice

BACKGROUND: Type 1 diabetes can be treated by the transplantation of cadaveric whole pancreata or isolated pancreatic islets. However, this form of treatment is hampered by the chronic shortage of cadaveric donors. Embryonic stem (ES) cell-derived insulin producing cells (IPCs) offer a potentially n...

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Detalles Bibliográficos
Autores principales:	Raikwar, Sudhanshu P, Zavazava, Nicholas
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2012
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3560994/ https://www.ncbi.nlm.nih.gov/pubmed/23369186 http://dx.doi.org/10.1186/2047-1440-1-19

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