Ribosome Traffic on mRNAs Maps to Gene Ontology: Genome-wide Quantification of Translation Initiation Rates and Polysome Size Regulation

To understand the complex relationship governing transcript abundance and the level of the encoded protein, we integrate genome-wide experimental data of ribosomal density on mRNAs with a novel stochastic model describing ribosome traffic dynamics during translation elongation. This analysis reveals...

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Detalles Bibliográficos
Autores principales: Ciandrini, Luca, Stansfield, Ian, Romano, M. Carmen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3561044/
https://www.ncbi.nlm.nih.gov/pubmed/23382661
http://dx.doi.org/10.1371/journal.pcbi.1002866

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3561044/
https://www.ncbi.nlm.nih.gov/pubmed/23382661
http://dx.doi.org/10.1371/journal.pcbi.1002866

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