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The [PSI (+)] Prion Exists as a Dynamic Cloud of Variants

[PSI (+)] is an amyloid-based prion of Sup35p, a subunit of the translation termination factor. Prion “strains” or “variants” are amyloids with different conformations of a single protein sequence, conferring different phenotypes, but each relatively faithfully propagated. Wild Saccharomyces cerevis...

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Detalles Bibliográficos
Autores principales: Bateman, David A., Wickner, Reed B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3561065/
https://www.ncbi.nlm.nih.gov/pubmed/23382698
http://dx.doi.org/10.1371/journal.pgen.1003257