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Nkx6.1 Controls a Gene Regulatory Network Required for Establishing and Maintaining Pancreatic Beta Cell Identity

All pancreatic endocrine cell types arise from a common endocrine precursor cell population, yet the molecular mechanisms that establish and maintain the unique gene expression programs of each endocrine cell lineage have remained largely elusive. Such knowledge would improve our ability to correctl...

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Detalles Bibliográficos
Autores principales: Schaffer, Ashleigh E., Taylor, Brandon L., Benthuysen, Jacqueline R., Liu, Jingxuan, Thorel, Fabrizio, Yuan, Weiping, Jiao, Yang, Kaestner, Klaus H., Herrera, Pedro L., Magnuson, Mark A., May, Catherine Lee, Sander, Maike
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3561089/
https://www.ncbi.nlm.nih.gov/pubmed/23382704
http://dx.doi.org/10.1371/journal.pgen.1003274