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Nkx6.1 Controls a Gene Regulatory Network Required for Establishing and Maintaining Pancreatic Beta Cell Identity
All pancreatic endocrine cell types arise from a common endocrine precursor cell population, yet the molecular mechanisms that establish and maintain the unique gene expression programs of each endocrine cell lineage have remained largely elusive. Such knowledge would improve our ability to correctl...
Autores principales: | Schaffer, Ashleigh E., Taylor, Brandon L., Benthuysen, Jacqueline R., Liu, Jingxuan, Thorel, Fabrizio, Yuan, Weiping, Jiao, Yang, Kaestner, Klaus H., Herrera, Pedro L., Magnuson, Mark A., May, Catherine Lee, Sander, Maike |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3561089/ https://www.ncbi.nlm.nih.gov/pubmed/23382704 http://dx.doi.org/10.1371/journal.pgen.1003274 |
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