An Incompatibility between a Mitochondrial tRNA and Its Nuclear-Encoded tRNA Synthetase Compromises Development and Fitness in Drosophila

Mitochondrial transcription, translation, and respiration require interactions between genes encoded in two distinct genomes, generating the potential for mutations in nuclear and mitochondrial genomes to interact epistatically and cause incompatibilities that decrease fitness. Mitochondrial-nuclear...

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Detalles Bibliográficos
Autores principales: Meiklejohn, Colin D., Holmbeck, Marissa A., Siddiq, Mohammad A., Abt, Dawn N., Rand, David M., Montooth, Kristi L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3561102/
https://www.ncbi.nlm.nih.gov/pubmed/23382693
http://dx.doi.org/10.1371/journal.pgen.1003238

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3561102/
https://www.ncbi.nlm.nih.gov/pubmed/23382693
http://dx.doi.org/10.1371/journal.pgen.1003238

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