Cargando…

Aberrant methylation of the M-type phospholipase A(2) receptor gene in leukemic cells

BACKGROUND: The M-type phospholipase A2 receptor (PLA2R1) plays a crucial role in several signaling pathways and may act as tumor-suppressor. This study examined the expression and methylation of the PLA2R1 gene in Jurkat and U937 leukemic cell lines and its methylation in patients with myelodysplas...

Descripción completa

Detalles Bibliográficos
Autores principales: Menschikowski, Mario, Platzbecker, Uwe, Hagelgans, Albert, Vogel, Margot, Thiede, Christian, Schönefeldt, Claudia, Lehnert, Renate, Eisenhofer, Graeme, Siegert, Gabriele
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3561142/
https://www.ncbi.nlm.nih.gov/pubmed/23217014
http://dx.doi.org/10.1186/1471-2407-12-576