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Aberrant methylation of the M-type phospholipase A(2) receptor gene in leukemic cells
BACKGROUND: The M-type phospholipase A2 receptor (PLA2R1) plays a crucial role in several signaling pathways and may act as tumor-suppressor. This study examined the expression and methylation of the PLA2R1 gene in Jurkat and U937 leukemic cell lines and its methylation in patients with myelodysplas...
Autores principales: | Menschikowski, Mario, Platzbecker, Uwe, Hagelgans, Albert, Vogel, Margot, Thiede, Christian, Schönefeldt, Claudia, Lehnert, Renate, Eisenhofer, Graeme, Siegert, Gabriele |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3561142/ https://www.ncbi.nlm.nih.gov/pubmed/23217014 http://dx.doi.org/10.1186/1471-2407-12-576 |
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