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24 Hours in the Life of HIV-1 in a T Cell Line

HIV-1 infects CD4+ T cells and completes its replication cycle in approximately 24 hours. We employed repeated measurements in a standardized cell system and rigorous mathematical modeling to characterize the emergence of the viral replication intermediates and their impact on the cellular transcrip...

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Detalles Bibliográficos
Autores principales: Mohammadi, Pejman, Desfarges, Sébastien, Bartha, István, Joos, Beda, Zangger, Nadine, Muñoz, Miguel, Günthard, Huldrych F., Beerenwinkel, Niko, Telenti, Amalio, Ciuffi, Angela
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3561177/
https://www.ncbi.nlm.nih.gov/pubmed/23382686
http://dx.doi.org/10.1371/journal.ppat.1003161