Inhibition of COX-2 expression by topical diclofenac enhanced radiation sensitivity via enhancement of TRAIL in human prostate adenocarcinoma xenograft model

BACKGROUND: COX-2 inhibitors have an antitumor potential and have been verified by many researchers. Treatment of cancer cells with external stressors such as irradiation can stimulate the over-expression of COX-2 and possibly confer radiation resistance. In this study, we tested if topical diclofen...

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Detalles Bibliográficos
Autores principales: Inoue, Takeshi, Anai, Satoshi, Onishi, Sayuri, Miyake, Makito, Tanaka, Nobumichi, Hirayama, Akihide, Fujimoto, Kiyohide, Hirao, Yoshihiko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3561196/
https://www.ncbi.nlm.nih.gov/pubmed/23289871
http://dx.doi.org/10.1186/1471-2490-13-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3561196/
https://www.ncbi.nlm.nih.gov/pubmed/23289871
http://dx.doi.org/10.1186/1471-2490-13-1

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