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Optimization of Multimeric Human Papillomavirus L2 Vaccines

We sought to define the protective epitopes within the amino terminus of human papillomavirus (HPV) type 16 minor capsid protein L2. Passive transfer of mice with rabbit antisera to HPV16 L2 peptides 17–36, 32–51 and 65–81 provided significant protection against vaginal HPV16 challenge, whereas anti...

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Detalles Bibliográficos
Autores principales: Jagu, Subhashini, Kwak, Kihyuck, Karanam, Balasubramanyam, Huh, Warner K., Damotharan, Vijayarangam, Chivukula, Sudha V., Roden, Richard B. S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3561222/
https://www.ncbi.nlm.nih.gov/pubmed/23383218
http://dx.doi.org/10.1371/journal.pone.0055538