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Cyclosporine A Impairs Nucleotide Binding Oligomerization Domain (Nod1)-Mediated Innate Antibacterial Renal Defenses in Mice and Human Transplant Recipients

Acute pyelonephritis (APN), which is mainly caused by uropathogenic Escherichia coli (UPEC), is the most common bacterial complication in renal transplant recipients receiving immunosuppressive treatment. However, it remains unclear how immunosuppressive drugs, such as the calcineurin inhibitor cycl...

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Detalles Bibliográficos
Autores principales: Tourneur, Emilie, Ben Mkaddem, Sanae, Chassin, Cécilia, Bens, Marcelle, Goujon, Jean-Michel, Charles, Nicolas, Pellefigues, Christophe, Aloulou, Meryem, Hertig, Alexandre, Monteiro, Renato C., Girardin, Stephen E., Philpott, Dana J., Rondeau, Eric, Elbim, Carole, Werts, Catherine, Vandewalle, Alain
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3561241/
https://www.ncbi.nlm.nih.gov/pubmed/23382681
http://dx.doi.org/10.1371/journal.ppat.1003152