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Cyclosporine A Impairs Nucleotide Binding Oligomerization Domain (Nod1)-Mediated Innate Antibacterial Renal Defenses in Mice and Human Transplant Recipients
Acute pyelonephritis (APN), which is mainly caused by uropathogenic Escherichia coli (UPEC), is the most common bacterial complication in renal transplant recipients receiving immunosuppressive treatment. However, it remains unclear how immunosuppressive drugs, such as the calcineurin inhibitor cycl...
Autores principales: | Tourneur, Emilie, Ben Mkaddem, Sanae, Chassin, Cécilia, Bens, Marcelle, Goujon, Jean-Michel, Charles, Nicolas, Pellefigues, Christophe, Aloulou, Meryem, Hertig, Alexandre, Monteiro, Renato C., Girardin, Stephen E., Philpott, Dana J., Rondeau, Eric, Elbim, Carole, Werts, Catherine, Vandewalle, Alain |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3561241/ https://www.ncbi.nlm.nih.gov/pubmed/23382681 http://dx.doi.org/10.1371/journal.ppat.1003152 |
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