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Synthesis and biological evaluation of propargyl acetate derivatives as anti-mycobacterial agents

BACKGROUND: The emergence of multidrug-resistant strains of Mycobacterium tuberculosis (Mtb) has intensified efforts to discover novel drugs for tuberculosis (TB) treatment. Targeting the persistent state of Mtb, a condition in which Mtb is resistant to conventional drug therapies, is of particular...

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Detalles Bibliográficos
Autores principales: Azerang, Parisa, Rezayan, Ali Hossein, Sardari, Soroush, Kobarfard, Farzad, Bayat, Mitra, Tabib, Kimia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3561248/
https://www.ncbi.nlm.nih.gov/pubmed/23351675
http://dx.doi.org/10.1186/2008-2231-20-90