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Synthesis and biological evaluation of propargyl acetate derivatives as anti-mycobacterial agents
BACKGROUND: The emergence of multidrug-resistant strains of Mycobacterium tuberculosis (Mtb) has intensified efforts to discover novel drugs for tuberculosis (TB) treatment. Targeting the persistent state of Mtb, a condition in which Mtb is resistant to conventional drug therapies, is of particular...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3561248/ https://www.ncbi.nlm.nih.gov/pubmed/23351675 http://dx.doi.org/10.1186/2008-2231-20-90 |