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Gains of ubiquitylation sites in highly conserved proteins in the human lineage

BACKGROUND: Post-translational modification of lysine residues of specific proteins by ubiquitin modulates the degradation, localization, and activity of these target proteins. Here, we identified gains of ubiquitylation sites in highly conserved regions of human proteins that occurred during human...

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Detalles Bibliográficos
Autores principales: Kim, Dong Seon, Hahn, Yoonsoo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3561281/
https://www.ncbi.nlm.nih.gov/pubmed/23157318
http://dx.doi.org/10.1186/1471-2105-13-306