Dual Short Upstream Open Reading Frames Control Translation of a Herpesviral Polycistronic mRNA

The Kaposi's sarcoma-associated herpesvirus (KSHV) protein kinase, encoded by ORF36, functions to phosphorylate cellular and viral targets important in the KSHV lifecycle and to activate the anti-viral prodrug ganciclovir. Unlike the vast majority of mapped KSHV genes, no viral transcript has b...

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Detalles Bibliográficos
Autores principales: Kronstad, Lisa M., Brulois, Kevin F., Jung, Jae U., Glaunsinger, Britt A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3561293/
https://www.ncbi.nlm.nih.gov/pubmed/23382684
http://dx.doi.org/10.1371/journal.ppat.1003156

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3561293/
https://www.ncbi.nlm.nih.gov/pubmed/23382684
http://dx.doi.org/10.1371/journal.ppat.1003156

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