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Dual Short Upstream Open Reading Frames Control Translation of a Herpesviral Polycistronic mRNA
The Kaposi's sarcoma-associated herpesvirus (KSHV) protein kinase, encoded by ORF36, functions to phosphorylate cellular and viral targets important in the KSHV lifecycle and to activate the anti-viral prodrug ganciclovir. Unlike the vast majority of mapped KSHV genes, no viral transcript has b...
Autores principales: | Kronstad, Lisa M., Brulois, Kevin F., Jung, Jae U., Glaunsinger, Britt A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3561293/ https://www.ncbi.nlm.nih.gov/pubmed/23382684 http://dx.doi.org/10.1371/journal.ppat.1003156 |
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