An Upstream Open Reading Frame Modulates Ebola Virus Polymerase Translation and Virus Replication

Ebolaviruses, highly lethal zoonotic pathogens, possess longer genomes than most other non-segmented negative-strand RNA viruses due in part to long 5′ and 3′ untranslated regions (UTRs) present in the seven viral transcriptional units. To date, specific functions have not been assigned to these UTR...

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Detalles Bibliográficos
Autores principales: Shabman, Reed S., Hoenen, Thomas, Groseth, Allison, Jabado, Omar, Binning, Jennifer M., Amarasinghe, Gaya K., Feldmann, Heinz, Basler, Christopher F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3561295/
https://www.ncbi.nlm.nih.gov/pubmed/23382680
http://dx.doi.org/10.1371/journal.ppat.1003147

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3561295/
https://www.ncbi.nlm.nih.gov/pubmed/23382680
http://dx.doi.org/10.1371/journal.ppat.1003147

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