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Imatinib Reverses Doxorubicin Resistance by Affecting Activation of STAT3-Dependent NF-κB and HSP27/p38/AKT Pathways and by Inhibiting ABCB1

Despite advances in cancer detection and prevention, a diagnosis of metastatic disease remains a death sentence due to the fact that many cancers are either resistant to chemotherapy (conventional or targeted) or develop resistance during treatment, and residual chemoresistant cells are highly metas...

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Detalles Bibliográficos
Autores principales: Sims, Jonathan T., Ganguly, Sourik S., Bennett, Holly, Friend, J. Woodrow, Tepe, Jessica, Plattner, Rina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3561297/
https://www.ncbi.nlm.nih.gov/pubmed/23383209
http://dx.doi.org/10.1371/journal.pone.0055509