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Imatinib Reverses Doxorubicin Resistance by Affecting Activation of STAT3-Dependent NF-κB and HSP27/p38/AKT Pathways and by Inhibiting ABCB1
Despite advances in cancer detection and prevention, a diagnosis of metastatic disease remains a death sentence due to the fact that many cancers are either resistant to chemotherapy (conventional or targeted) or develop resistance during treatment, and residual chemoresistant cells are highly metas...
Autores principales: | Sims, Jonathan T., Ganguly, Sourik S., Bennett, Holly, Friend, J. Woodrow, Tepe, Jessica, Plattner, Rina |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3561297/ https://www.ncbi.nlm.nih.gov/pubmed/23383209 http://dx.doi.org/10.1371/journal.pone.0055509 |
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