Cargando…

Asymmetric N-Cadherin Expression Results in Synapse Dysfunction, Synapse Elimination, and Axon Retraction in Cultured Mouse Neurons

Synapse elimination and pruning of axon collaterals are crucial developmental events in the refinement of neuronal circuits. While a control of synapse formation by adhesion molecules is well established, the involvement of adhesion molecules in developmental synapse loss is poorly characterized. To...

Descripción completa

Detalles Bibliográficos
Autores principales: Pielarski, Kim N., van Stegen, Bernd, Andreyeva, Aksana, Nieweg, Katja, Jüngling, Kay, Redies, Christoph, Gottmann, Kurt
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3561303/
https://www.ncbi.nlm.nih.gov/pubmed/23382872
http://dx.doi.org/10.1371/journal.pone.0054105