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Purification and SAXS Analysis of the Integrin Linked Kinase, PINCH, Parvin (IPP) Heterotrimeric Complex

The heterotrimeric protein complex containing the integrin linked kinase (ILK), parvin, and PINCH proteins, termed the IPP complex, is an essential component of focal adhesions, where it interacts with many proteins to mediate signaling from integrin adhesion receptors. Here we conduct a biochemical...

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Detalles Bibliográficos
Autores principales: Stiegler, Amy L., Grant, Thomas D., Luft, Joseph R., Calderwood, David A., Snell, Edward H., Boggon, Titus J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3561323/
https://www.ncbi.nlm.nih.gov/pubmed/23383235
http://dx.doi.org/10.1371/journal.pone.0055591