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Protective Effects of SKF-96365, a Non-Specific Inhibitor of SOCE, against MPP(+)-Induced Cytotoxicity in PC12 Cells: Potential Role of Homer1

Parkinson's disease (PD) is the most common neurodegenerative movement disorder, characterized by loss of dopominergic (DA) neurons in substantia nigra pars compacta (SNpc), and can be experimentally mimicked by the neurotoxin MPP(+) in vitro models. In this study, we investigated the potential...

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Detalles Bibliográficos
Autores principales: Chen, Tao, Zhu, Jie, Zhang, Chi, Huo, Kai, Fei, Zhou, Jiang, Xiao-fan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3561331/
https://www.ncbi.nlm.nih.gov/pubmed/23383239
http://dx.doi.org/10.1371/journal.pone.0055601