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Combining Functional and Structural Genomics to Sample the Essential Burkholderia Structome

BACKGROUND: The genus Burkholderia includes pathogenic gram-negative bacteria that cause melioidosis, glanders, and pulmonary infections of patients with cancer and cystic fibrosis. Drug resistance has made development of new antimicrobials critical. Many approaches to discovering new antimicrobials...

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Detalles Bibliográficos
Autores principales: Baugh, Loren, Gallagher, Larry A., Patrapuvich, Rapatbhorn, Clifton, Matthew C., Gardberg, Anna S., Edwards, Thomas E., Armour, Brianna, Begley, Darren W., Dieterich, Shellie H., Dranow, David M., Abendroth, Jan, Fairman, James W., Fox, David, Staker, Bart L., Phan, Isabelle, Gillespie, Angela, Choi, Ryan, Nakazawa-Hewitt, Steve, Nguyen, Mary Trang, Napuli, Alberto, Barrett, Lynn, Buchko, Garry W., Stacy, Robin, Myler, Peter J., Stewart, Lance J., Manoil, Colin, Van Voorhis, Wesley C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3561365/
https://www.ncbi.nlm.nih.gov/pubmed/23382856
http://dx.doi.org/10.1371/journal.pone.0053851