A Novel SCN9A Mutation Responsible for Primary Erythromelalgia and Is Resistant to the Treatment of Sodium Channel Blockers

Primary erythromelalgia (PE) is an autosomal dominant neurological disorder characterized by severe burning pain and erythema in the extremities upon heat stimuli or exercise. Mutations in human SCN9A gene, encoding the α–subunit of the voltage-gated sodium channel, Na(v)1.7, were found to be respon...

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Detalles Bibliográficos
Autores principales: Wu, Min-Tzu, Huang, Po-Yuan, Yen, Chen-Tung, Chen, Chih-Cheng, Lee, Ming-Jen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3561374/
https://www.ncbi.nlm.nih.gov/pubmed/23383113
http://dx.doi.org/10.1371/journal.pone.0055212

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3561374/
https://www.ncbi.nlm.nih.gov/pubmed/23383113
http://dx.doi.org/10.1371/journal.pone.0055212

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