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The MAPK Pathway Signals Telomerase Modulation in Response to Isothiocyanate-Induced DNA Damage of Human Liver Cancer Cells

4-methylthiobutyl isothiocyanate (MTBITC), an aliphatic, sulphuric compound from Brassica vegetables, possesses in vitro and in vivo antitumor activity. Recently we demonstrated the potent growth inhibitory potential of the DNA damaging agent MTBITC in human liver cancer cells. Here we now show that...

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Detalles Bibliográficos
Autores principales: Lamy, Evelyn, Herz, Corinna, Lutz-Bonengel, Sabine, Hertrampf, Anke, Márton, Melinda-Rita, Mersch-Sundermann, Volker
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3561400/
https://www.ncbi.nlm.nih.gov/pubmed/23382840
http://dx.doi.org/10.1371/journal.pone.0053240