Cargando…
The MAPK Pathway Signals Telomerase Modulation in Response to Isothiocyanate-Induced DNA Damage of Human Liver Cancer Cells
4-methylthiobutyl isothiocyanate (MTBITC), an aliphatic, sulphuric compound from Brassica vegetables, possesses in vitro and in vivo antitumor activity. Recently we demonstrated the potent growth inhibitory potential of the DNA damaging agent MTBITC in human liver cancer cells. Here we now show that...
Autores principales: | Lamy, Evelyn, Herz, Corinna, Lutz-Bonengel, Sabine, Hertrampf, Anke, Márton, Melinda-Rita, Mersch-Sundermann, Volker |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3561400/ https://www.ncbi.nlm.nih.gov/pubmed/23382840 http://dx.doi.org/10.1371/journal.pone.0053240 |
Ejemplares similares
-
The isothiocyanate erucin abrogates telomerase in hepatocellular carcinoma cells in vitro and in an orthotopic xenograft tumour model of HCC
por: Herz, Corinna, et al.
Publicado: (2014) -
Preclinical Evaluation of 4-Methylthiobutyl Isothiocyanate on Liver Cancer and Cancer Stem Cells with Different p53 Status
por: Lamy, Evelyn, et al.
Publicado: (2013) -
Allyl Isothiocyanate: A TAS2R38 Receptor-Dependent Immune Modulator at the Interface Between Personalized Medicine and Nutrition
por: Tran, Hoai T. T., et al.
Publicado: (2021) -
Low-dose levels of bisphenol A inhibit telomerase via ER/GPR30-ERK signalling, impair DNA integrity and reduce cell proliferation in primary PBMC
por: Herz, Corinna, et al.
Publicado: (2017) -
Evaluation of an Aqueous Extract from Horseradish Root (Armoracia rusticana Radix) against Lipopolysaccharide-Induced Cellular Inflammation Reaction
por: Herz, Corinna, et al.
Publicado: (2017)