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Inositol Pyrophosphate Synthesis by Inositol Hexakisphosphate Kinase 1 Is Required for Homologous Recombination Repair

Inositol pyrophosphates, such as diphosphoinositol pentakisphosphate (IP(7)), are water-soluble inositol phosphates that contain high energy diphosphate moieties on the inositol ring. Inositol hexakisphosphate kinase 1 (IP6K1) participates in inositol pyrophosphate synthesis, converting inositol hex...

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Detalles Bibliográficos
Autores principales: Jadav, Rathan S., Chanduri, Manasa V. L., Sengupta, Sagar, Bhandari, Rashna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3561551/
https://www.ncbi.nlm.nih.gov/pubmed/23255604
http://dx.doi.org/10.1074/jbc.M112.396556