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Molecular Architecture and Functional Analysis of NetB, a Pore-forming Toxin from Clostridium perfringens

NetB is a pore-forming toxin produced by Clostridium perfringens and has been reported to play a major role in the pathogenesis of avian necrotic enteritis, a disease that has emerged due to the removal of antibiotics in animal feedstuffs. Here we present the crystal structure of the pore form of Ne...

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Detalles Bibliográficos
Autores principales: Savva, Christos G., Fernandes da Costa, Sérgio P., Bokori-Brown, Monika, Naylor, Claire E., Cole, Ambrose R., Moss, David S., Titball, Richard W., Basak, Ajit K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3561570/
https://www.ncbi.nlm.nih.gov/pubmed/23239883
http://dx.doi.org/10.1074/jbc.M112.430223