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The Sulfonylurea Receptor 1 (Sur1)-Transient Receptor Potential Melastatin 4 (Trpm4) Channel

The sulfonylurea receptor 1 (Sur1)-NC(Ca-ATP) channel plays a central role in necrotic cell death in central nervous system (CNS) injury, including ischemic stroke, and traumatic brain and spinal cord injury. Here, we show that Sur1-NC(Ca-ATP) channels are formed by co-assembly of Sur1 and transient...

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Detalles Bibliográficos
Autores principales: Woo, Seung Kyoon, Kwon, Min Seong, Ivanov, Alexander, Gerzanich, Volodymyr, Simard, J. Marc
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3561583/
https://www.ncbi.nlm.nih.gov/pubmed/23255597
http://dx.doi.org/10.1074/jbc.M112.428219