Modulation of the Unfolded Protein Response During Hepatocyte and Cardiomyocyte Apoptosis In Trauma/Hemorrhagic Shock

Trauma with hemorrhagic shock (T/HS), has been shown to result in liver injury marked by hepatocyte apoptosis and heart failure marked by cardiomyocyte apoptosis, both of which we have shown to be prevented by IL-6 administration at resuscitation, and Stat3 largely mediated this. As specific mediato...

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Detalles Bibliográficos
Autores principales: Thacker, Stephen A., Robinson, Prema, Abel, Adam, Tweardy, David J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2013
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3561621/
https://www.ncbi.nlm.nih.gov/pubmed/23378918
http://dx.doi.org/10.1038/srep01187

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3561621/
https://www.ncbi.nlm.nih.gov/pubmed/23378918
http://dx.doi.org/10.1038/srep01187

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