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Src activation by β-adrenoreceptors is a key switch for tumor metastasis

Norepinephrine (NE) can modulate multiple cellular functions important for cancer progression; however, how this single extracellular signal regulates such a broad array of cellular processes is unknown. Here, we identify Src as a key regulator of phosphoproteomic signaling networks activated in res...

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Detalles Bibliográficos
Autores principales: Armaiz-Pena, Guillermo N., Allen, Julie K., Cruz, Anthony, Stone, Rebecca L., Nick, Alpa M., Lin, Yvonne G., Han, Liz Y., Mangala, Lingegowda S., Villares, Gabriel J., Vivas-Mejia, Pablo, Rodriguez-Aquayo, Cristian, Nagaraja, Archana S., Gharpure, Kshipra M., Wu, Zheng, English, Robert D., Soman, Kizhake V., Shazhad, Mian M. K., Zigler, Maya, Deavers, Michael T., Zien, Alexander, Soldatos, Theodoros G., Jackson, David B., Wiktorowicz, John E., Torres-Lugo, Madeline, Young, Tom, De Geest, Koen, Gallick, Gary E., Bar-Eli, Menashe, Lopez-Berestein, Gabriel, Cole, Steve W., Lopez, Gustavo E., Lutgendorf, Susan K., Sood, Anil K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3561638/
https://www.ncbi.nlm.nih.gov/pubmed/23360994
http://dx.doi.org/10.1038/ncomms2413