Statistical optimization of a novel excipient (CMEC) based gastro retentive floating tablets of propranolol HCl and it’s in vivo buoyancy characterization in healthy human volunteers

The objective of the present investigation is to formulate gastro retentive floating drug delivery systems (GRFDDS) of propranolol HCl by central composite design and to study the effect of formulation variables on floating lag time, D(1hr) (% drug release at 1 hr) and t(90) (time required to releas...

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Detalles Bibliográficos
Autores principales: Meka, Venkata Srikanth, Nali, Sreenivasa Rao, Songa, Ambedkar Sunil, Battu, Janaki Ram, Kolapalli, Venkata Ramana Murthy
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3561659/
https://www.ncbi.nlm.nih.gov/pubmed/23351981
http://dx.doi.org/10.1186/2008-2231-20-21

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3561659/
https://www.ncbi.nlm.nih.gov/pubmed/23351981
http://dx.doi.org/10.1186/2008-2231-20-21

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