Microdomains of muscarinic acetylcholine and Ins(1,4,5)P(3) receptors create ‘Ins(1,4,5)P(3) junctions’ and sites of Ca(2+) wave initiation in smooth muscle

Increases in cytosolic Ca(2+) concentration ([Ca(2+)](c)) mediated by inositol (1,4,5)-trisphosphate [Ins(1,4,5)P(3), hereafter InsP(3)] regulate activities that include division, contraction and cell death. InsP(3)-evoked Ca(2+) release often begins at a single site, then regeneratively propagates...

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Detalles Bibliográficos
Autores principales: Olson, Marnie L., Sandison, Mairi E., Chalmers, Susan, McCarron, John G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3561854/
https://www.ncbi.nlm.nih.gov/pubmed/22946060
http://dx.doi.org/10.1242/jcs.105163

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3561854/
https://www.ncbi.nlm.nih.gov/pubmed/22946060
http://dx.doi.org/10.1242/jcs.105163

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