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Constitutive nuclear lamina–genome interactions are highly conserved and associated with A/T-rich sequence
In metazoans, the nuclear lamina is thought to play an important role in the spatial organization of interphase chromosomes, by providing anchoring sites for large genomic segments named lamina-associated domains (LADs). Some of these LADs are cell-type specific, while many others appear constitutiv...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cold Spring Harbor Laboratory Press
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3561868/ https://www.ncbi.nlm.nih.gov/pubmed/23124521 http://dx.doi.org/10.1101/gr.141028.112 |