Constitutive nuclear lamina–genome interactions are highly conserved and associated with A/T-rich sequence

In metazoans, the nuclear lamina is thought to play an important role in the spatial organization of interphase chromosomes, by providing anchoring sites for large genomic segments named lamina-associated domains (LADs). Some of these LADs are cell-type specific, while many others appear constitutiv...

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Detalles Bibliográficos
Autores principales: Meuleman, Wouter, Peric-Hupkes, Daan, Kind, Jop, Beaudry, Jean-Bernard, Pagie, Ludo, Kellis, Manolis, Reinders, Marcel, Wessels, Lodewyk, van Steensel, Bas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2013
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3561868/
https://www.ncbi.nlm.nih.gov/pubmed/23124521
http://dx.doi.org/10.1101/gr.141028.112

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