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Mesenchymal stem cells overexpressing PEDF decrease the angiogenesis of gliomas

The present study is an exploration of a novel strategy to target a therapeutic gene to brain tumour tissues. In the present study, we evaluated the feasibility of using hMSCs (human mesenchymal stem cells) to deliver PEDF (pigment epithelium-derived factor), a potent inhibitor of tumour angiogenesi...

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Detalles Bibliográficos
Autores principales: Wang, Qiaoshu, Zhang, Zhaoyun, Ding, Tianling, Chen, Zi, Zhang, Tao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Portland Press Ltd. 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3561916/
https://www.ncbi.nlm.nih.gov/pubmed/22917444
http://dx.doi.org/10.1042/BSR20110124