Improved nucleic acid descriptors for siRNA efficacy prediction

Although considerable progress has been made recently in understanding how gene silencing is mediated by the RNAi pathway, the rational design of effective sequences is still a challenging task. In this article, we demonstrate that including three-dimensional descriptors improved the discrimination...

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Detalles Bibliográficos
Autores principales: Sciabola, Simone, Cao, Qing, Orozco, Modesto, Faustino, Ignacio, Stanton, Robert V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2013
Materias:
Computational Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3561943/
https://www.ncbi.nlm.nih.gov/pubmed/23241392
http://dx.doi.org/10.1093/nar/gks1191

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3561943/
https://www.ncbi.nlm.nih.gov/pubmed/23241392
http://dx.doi.org/10.1093/nar/gks1191

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