Differential strand separation at critical temperature: A minimally disruptive enrichment method for low-abundance unknown DNA mutations

Detection of low-level DNA variations in the presence of wild-type DNA is important in several fields of medicine, including cancer, prenatal diagnosis and infectious diseases. PCR-based methods to enrich mutations during amplification have limited multiplexing capability, are mostly restricted to k...

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Detalles Bibliográficos
Autores principales: Guha, Minakshi, Castellanos-Rizaldos, Elena, Liu, Pingfang, Mamon, Harvey, Makrigiorgos, G. Mike
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2013
Materias:
Methods Online
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3561944/
https://www.ncbi.nlm.nih.gov/pubmed/23258702
http://dx.doi.org/10.1093/nar/gks1250

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3561944/
https://www.ncbi.nlm.nih.gov/pubmed/23258702
http://dx.doi.org/10.1093/nar/gks1250

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