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Differential strand separation at critical temperature: A minimally disruptive enrichment method for low-abundance unknown DNA mutations
Detection of low-level DNA variations in the presence of wild-type DNA is important in several fields of medicine, including cancer, prenatal diagnosis and infectious diseases. PCR-based methods to enrich mutations during amplification have limited multiplexing capability, are mostly restricted to k...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Oxford University Press
2013
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3561944/ https://www.ncbi.nlm.nih.gov/pubmed/23258702 http://dx.doi.org/10.1093/nar/gks1250 |