Competing roles of DNA end resection and non-homologous end joining functions in the repair of replication-born double-strand breaks by sister-chromatid recombination

While regulating the choice between homologous recombination and non-homologous end joining (NHEJ) as mechanisms of double-strand break (DSB) repair is exerted at several steps, the key step is DNA end resection, which in Saccharomyces cerevisiae is controlled by the MRX complex and the Sgs1 DNA hel...

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Detalles Bibliográficos
Autores principales: Muñoz-Galván, Sandra, López-Saavedra, Ana, Jackson, Stephen P., Huertas, Pablo, Cortés-Ledesma, Felipe, Aguilera, Andrés
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2013
Materias:
Genome Integrity, Repair and Replication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3561951/
https://www.ncbi.nlm.nih.gov/pubmed/23254329
http://dx.doi.org/10.1093/nar/gks1274

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3561951/
https://www.ncbi.nlm.nih.gov/pubmed/23254329
http://dx.doi.org/10.1093/nar/gks1274

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